Polymerase Chain Reaction (PCR) Amplification of the Individual DNA Fragments Forming the Chimera and to Generate the Chimeric DNA Sequence
9:22
Results: Generation of the Oncostatin M BC Loop Chimera
10:55
Conclusion
Transcription
Exchanging regions of structurally similar proteins to create kimeras allows us to investigate the importance of regions responsible for biological functions of the molecule to be studied. Region exchanges predoff the general secondary structure o
Connectez-vous ou commencez votre essai gratuit pour accéder à ce contenu.
Structurally related proteins frequently exert distinct biological functions. The exchange of equivalent regions of these proteins in order to create chimeric proteins constitutes an innovative approach to identify critical protein regions that are responsible for their functional divergence.