Transformation of Toxic Yeast with the Yeast Genomic Library
5:44
Results: Yeast Suppressor Screen
6:48
Conclusion
Transcription
Intracellular bacteria secrete effector proteins into the host that can manipulate biological pathways to promote pathogen survival. Revealing host targets of effectors is essential for understanding intracellular pathogens like Chlamydia trachoma
Connectez-vous ou commencez votre essai gratuit pour accéder à ce contenu.
Bacterial pathogens secrete proteins into the host that target crucial biological processes. Identifying the host pathways targeted by bacterial effector proteins is key to addressing molecular pathogenesis. Here, a method using a modified yeast suppressor and toxicity screen to elucidate host pathways targeted by toxic bacterial effector proteins is described.