Results: Uptake of Fluorescent Labeled Small Extracellular Vesicles
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Conclusion
Transcription
Visualizing uptake of small extracellular vesicles, also known as sEVs, by different cells in the spinal cord, can confirm a successful delivery of sEVs. This enables both mechanistic and therapeutic studies of intrathecally administered sEVs from
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We describe a protocol to label macrophage-derived small extracellular vesicles with PKH dyes and observe their uptake in vitro and in the spinal cord after intrathecal delivery.