Results: FMRP Knockdown in the Chicken NM and Auditory Duct and Axonal Tracking of Transfected AG Neurons in the Brainstem
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Conclusion
Transcription
Our protocol is an in vivo method to investigate the cell-autonomous functions of FMRP during development. This can help to understand the cell type-specific pathophysiology of fragile X syndrome. This method employs stage, site, and direction-spe
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Using in ovo electroporation, we devised a method to selectively transfect the auditory inner ear and cochlear nucleus in chicken embryos to achieve a cell-group-specific knockdown of fragile X mental retardation protein during discrete periods of circuit assembly.