The overall goal of this video is to provide a step-by-step instruction on how to measure the isometric tetanic force of the tibialis anterior muscle in the rat, a reproducible and validated method to assess functional recovery after sciatic nerve
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Evaluation of motor recovery remains the benchmark outcome measure in experimental peripheral nerve studies. The isometric tetanic force measurement of the tibialis anterior muscle in the rat is an invaluable tool to assess functional outcomes after reconstruction of sciatic nerve defects. The methods and nuances are detailed in this article.