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JoVE Journal

Medicine

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Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

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08:58 min

May 21st, 2013

May 21st, 2013

14,258 Views

0:05

Title

1:31

Cartilage Biopsy

3:01

In vitro Culture

5:01

Cell-seeding of the Matrix

6:09

Matrix-assisted Autologous Chondrocyte Transplantation

7:26

Results: Successful Isolation and Implantation of Autologous Chondrocytes into an Artificial Chondral Defect

8:12

Conclusion

An experimental technique for the treatment of chondral defects in the rabbit's knee joint is described. The implantation of autologous chondrocytes seeded on a matrix is a well-accepted method for the remodeling and repair of articular cartilage lesions providing satisfying long-term results. Matrix-assisted autologous chondrocyte transplantation (MACT) offers a standardized and clinically established implantation method.

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