Results: Successful Delivery of pCAG-GFP Plasmid to the Mouse Bladder Urothelium
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Conclusion
필기록
The overall goal of this method is to deliver DNA plasmids into the bladder urothelium of live mice in vivo for gene overexpression or genome editing. This method can help answer key questions in the bladder cancer field, such as how do different
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We describe a novel method for the delivery of DNA plasmid into the urothelial cells of mouse bladder in vivo through urethra catheterization and electroporation. It offers a fast and convenient way for generating autochthonous mouse models of bladder diseases.