Methods Article

Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes

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7.6K Views

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08:07 min

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March 9th, 2019

DOI :

10.3791/58998-v

March 9th, 2019

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Joseph S. Najem¹^,², Graham J. Taylor²^,³, Nick Armendarez⁴, Ryan J. Weiss⁵, Md Sakib Hasan⁵, Garrett S. Rose⁵, Catherine D. Schuman⁶, Alex Belianinov⁷, Stephen A. Sarles², C. Patrick Collier²^,³^,⁷

¹Joint Institute for Biological Sciences, Oak Ridge National Laboratory, ²Department of Mechanical, Aerospace and Biomedical Engineering, University of Tennessee, ³Bredesen Center for Interdisciplinary Research, University of Tennessee, ⁴Department of Biosystems and Agriculture Engineering, University of Kentucky, ⁵Department of Electrical Engineering and Computer Science, University of Tennessee, ⁶Computer Science and Mathematics Division, Oak Ridge National Laboratory, ⁷Center for Nanophase Materials Sciences, Oak Ridge National Laboratory

요약

Soft, low-power, biomolecular memristors leverage similar composition, structure, and switching mechanisms of bio-synapses. Presented here is a protocol to assemble and characterize biomolecular memristors obtained from insulating lipid bilayers formed between water droplets in oil. The incorporation of voltage-activated alamethicin peptides results in memristive ionic conductance across the membrane.

더 많은 비디오 탐색

Biomolecular Memristors

Ion Channel doped Lipid Membranes

Peptide doped Biomembrane

Memory Resistance

Short term Plasticity

Lipid Bilayer Formation

Alamethicin

Liposome Solutions

Droplet Interface Bilayer

Cellular Transport Processes

Voltage activated Ion Channels