Results: Functional Activity and Effects of Mechanically Induced Strain
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Conclusion
Transcrição
Here we present protocols for culturing bone cells within an adaptable lab-on-a-chip platform. These techniques can be used to further our understanding of the mechanisms that regulate mechanically-induced bone remodeling. Our system allows for lo
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Here, we present protocols for analyzing bone remodeling within a lab-on-a-chip platform. A 3D printed mechanical loading device can be paired with the platform to induce osteocyte mechanostransduction by deforming the cellular matrix. The platform can also be used to quantify bone remodeling functional outcomes from osteoclasts and osteoblasts (resorption/formation).