Results: Glutamate Receptor Trafficking in Dissociated Primary Hippocampal Cultures
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Conclusion
Transkript
Cellular responses to external stimuli heavily rely on the set of proteins that are expressed on the cell surface in a given moment. Accordingly, the number, the sub-cellular localization, and subunit composition of these proteins are dynamically
Bu içeriğe erişmek için giriş yapın veya ücretsiz denemenizi başlatın
This article presents a method to study glutamate receptor (GluR) trafficking in dissociated primary hippocampal cultures. Using an antibody-feeding approach to label endogenous or overexpressed receptors in combination with pharmacological approaches, this method allows for the identification of molecular mechanisms regulating GluR surface expression by modulating internalization or recycling processes.