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Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice

DOI :

10.3791/2618-v

August 24th, 2011

August 24th, 2011

14,355 Views

1Department of Neurology, University of Connecticut Health Center, 2Department of Neurology, School of Medicine, University of Pennsylvania, 3Department of Neurosurgery, Hartford Hospital, 4Department of Neurosurgery, School of Medicine, University of Pennsylvania

The autologous blood injection model of intracerebral hemorrhage in mice described in this protocol uses the double injection technique to minimize risk of blood reflux up the needle track, no anticoagulants in the pumping system, and eliminates all dead space and expandable tubing in the system.

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Autologous Blood Injection

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