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Chromatin Isolation by RNA Purification (ChIRP)

DOI :

10.3791/3912-v

11:09 min

March 25th, 2012

March 25th, 2012

84,009 Views

1Howard Hughes Medical Institute and Program in Epithelial Biology, Stanford University School of Medicine

ChIRP is a novel and rapid technique to map genomic binding sites of long noncoding RNAs (lncRNAs). The method takes advantage of the specificity of anti-sense tiling oligonucleotides to allow the enumeration of lncRNA-bound genomic sites.

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Chromatin Isolation By RNA Purification

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