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Non-invasive Imaging of Disseminated Candidiasis in Zebrafish Larvae

DOI :

10.3791/4051-v

July 30th, 2012

July 30th, 2012

14,493 Views

1Department of Molecular and Biomedical Sciences, University of Maine

The rapid development, small size and transparency of zebrafish are tremendous advantages for the study of innate immune control of infection1-4. Here we demonstrate techniques for infecting zebrafish larvae using the fungal pathogen Candida albicans by microinjection, methodology recently used to implicate phagocyte NADPH oxidase activity in control of fungal dimorphism5.

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Non invasive Imaging

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