JoVE Logo
Faculty Resource Center

Sign In

DNA Vector-based RNA Interference to Study Gene Function in Cancer

DOI :

10.3791/4129-v

June 4th, 2012

June 4th, 2012

20,205 Views

1Department of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, 2Department of Pathology and Comprehensive Cancer Center, Wake Forest University School of Medicine

RNA interference (RNAi) possesses many advantages over gene knockout and has been broadly used as a tool in gene functional studies. The invention of DNA vector-based RNAi technology has made long term and inducible gene knockdown possible, and also increased the feasibility of gene silencing in vivo.

-- Views

Related Videos

article

In Vivo Canine Muscle Function Assay

article

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

article

An In Vitro System to Study Tumor Dormancy and the Switch to Metastatic Growth

article

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

article

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

article

Noninvasive Intratracheal Intubation to Study the Pathology and Physiology of Mouse Lung

article

Three Dimensional Cultures: A Tool To Study Normal Acinar Architecture vs. Malignant Transformation Of Breast Cells

article

An Ex vivo Model to Study Hormone Action in the Human Breast

article

In Vivo and Ex Vivo Approaches to Study Ovarian Cancer Metastatic Colonization of Milky Spot Structures in Peritoneal Adipose

article

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved