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An In Vitro System to Study Tumor Dormancy and the Switch to Metastatic Growth

DOI :

10.3791/2914-v

August 11th, 2011

August 11th, 2011

15,583 Views

1Department of Biology, University of Haifa, 2Transgenic Oncogenesis and Genomics Section, Laboratory of Cancer Biology and Genetics, National Cancer Institute

A modified 3-D in vitro system is presented in which growth characteristics of several tumor cell lines in reconstituted basement membrane correlate with the dormant or proliferative behavior of the tumor cells at a metastatic secondary site in vivo.

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In Vitro System

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