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The Citrobacter rodentium Mouse Model: Studying Pathogen and Host Contributions to Infectious Colitis

DOI :

10.3791/50222-v

February 19th, 2013

February 19th, 2013

25,629 Views

1Division of Gastroenterology, BC Children's Hospital

Citrobacter rodentium infection provides a valuable model to study enteric bacterial infections as well as host immune responses and colitis in mice. This protocol outlines the measurement of barrier integrity, pathogen load and histological damage allowing for the thorough characterization of pathogen and host contributions to murine infectious colitis.

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