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Complete Thymectomy in Adult Rats with Non-invasive Endotracheal Intubation

DOI :

10.3791/52152-v

December 29th, 2014

December 29th, 2014

16,116 Views

1Department of Surgery, Duke University Medical Center, 2Department of Pediatrics, Duke University Medical Center, 3Department of Immunology, Duke University Medical Center

Rodent thymectomy is a valuable technique in immunological research. Here, a protocol for complete thymectomy in adult rats using a mini-sternotomy along with non-invasive intubation and positive pressure ventilation to minimize perioperative morbidity and mortality is described.

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Thymectomy

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