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A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice

DOI :

10.3791/52640-v

March 17th, 2015

March 17th, 2015

14,341 Views

1MSTP, Neuroscience Program, Washington University in St. Louis, 2Washington University Pain Center, Department of Anesthesiology, Washington University in St. Louis

The Cold Plantar Assay (CPA) measures cold responsiveness between 30 °C and 5 °C, and can also measure cold adaptation. This protocol describes how to use the CPA to measure cold hypersensitivity, analgesia, and adaptation in mice.

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Cold Sensitivity

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