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Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

8.9K Views

09:42 min

January 16th, 2016

DOI :

10.3791/53168-v

January 16th, 2016


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Keywords Enzyme Catalysis

Chapters in this video

0:05

Title

1:00

In Silico Computer Modeling

2:02

Model of Active Site Solvation and Water Access

3:02

In Silico Enzyme Engineering to Modify Water Patterns and Water Dynamics

3:56

Membrane Extracton Using a Normal Centrifuge and Protein Purification

5:10

Kinetics

6:20

Extraction and Thermodynamic Analysis

8:20

Results: Impact of Water Dynamics on Enzyme Catalysis

9:10

Conclusion

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