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Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs

DOI :

10.3791/54039-v

7:31 min

May 24th, 2016

May 24th, 2016

17,051 Views

1Brain Tumor Center & Neuro-Oncology Unit, Department of Neurology, Beth Israel Deaconess Medical Center & Harvard Medical School, 2Division of Cancer Genetics, Department of Medicine, Beth Israel Deaconess Medical Center & Harvard Medical School

Metastasis plays a profound role in the virulence of cancer, accounting for an estimated 90% of deaths. We report a protocol for a metastatic melanoma model in mice that is useful for determining the efficacy of therapeutic agents against this clinical phenomenon.

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