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Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration

DOI :

10.3791/54100-v

May 24th, 2016

May 24th, 2016

17,101 Views

1Department of Physiology and Pharmacology, Western University

This protocol describes a highly reproducible model of cardiac regeneration by surgical induction of myocardial infarction in the left ventricle of postnatal day 1 mice. The method involves induction of hypothermic anesthesia and ligation of the left anterior descending coronary artery.

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