Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b

8.4K Views

10:20 min

November 11th, 2016

DOI :

10.3791/54540-v

November 11th, 2016


Transcript

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Small Molecule Inhibitors

Chapters in this video

0:05

Title

1:08

High Throughput Screen

3:07

Confirmation of Hits Using TAMRA-tagged HCN1 Peptide

4:33

Dose-response Validation of Bead-based Proximity Assay

7:15

Results: Identification of Small Molecule Inhibitors Between HCN1 and TRIPb8 Interactions

9:14

Conclusion

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