Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones

12.4K Views

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11:43 min

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November 30th, 2016

DOI :

10.3791/54657-v

November 30th, 2016

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Go Oshima*¹^,², Melinda E. Stack*¹, Sean C. Wightman¹, Darren Bryan¹, Elizabeth Poli¹, Lai Xue¹, Kinga B. Skowron¹, Abhineet Uppal¹, Sean P. Pitroda², Xiaona Huang², Mitchell C. Posner¹, Samuel Hellman², Ralph R. Weichselbaum², Nikolai N. Khodarev²

¹Department of Surgery, The University of Chicago, ²Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, The University of Chicago

Summary

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Keywords Colorectal Cancer

Chapters in this video

0:05

Title

1:14

Calibration of Fluorescent Signal Intensity as a Function of Cell Number

2:29

Animal Model of Liver Metastases

5:44

In Vivo Bioluminescent Imaging

7:58

Ex Vivo Fluorescent Imaging

9:05

Results: Metastases and Differential Liver Colonization of Colorectal Cancer Cells

10:34

Conclusion

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