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A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer

DOI :

10.3791/54903-v

7:35 min

December 26th, 2016

December 26th, 2016

38,732 Views

1Department of Cell, Developmental and Cancer Biology, Oregon Health and Science University

A surgical procedure was developed to deliver mammary tumor cells to the murine liver via portal vein injection. This model permits investigation of late stages of liver metastasis in a fully immune competent host, including tumor cell extravasation, seeding, survival, and metastatic outgrowth in the liver.

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Portal Vein Injection Model

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