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A High-throughput Cell Microarray Platform for Correlative Analysis of Cell Differentiation and Traction Forces

DOI :

10.3791/55362-v

12:04 min

March 1st, 2017

March 1st, 2017

9,246 Views

1Department of Bioengineering, University of Illinois at Urbana–Champaign

Cell differentiation is regulated by a host of microenvironmental factors, including both matrix composition and substrate material properties. We describe here a technique utilizing cell microarrays in conjunction with traction force microscopy to evaluate both cell differentiation and biomechanical cell–substrate interactions as a function of microenvironmental context.

Tags

High throughput

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