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Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein

DOI :

10.3791/57021-v

8:26 min

June 12th, 2018

June 12th, 2018

8,900 Views

1Division of Cancer Stem Cell, National Cancer Center Research Institute

Human telomerase reverse transcriptase (TERT) synthesizes not only telomeric DNA but also double-stranded RNA through RNA-dependent RNA polymerase activity. Here, we describe a newly established assay to detect RNA-dependent RNA polymerase activity of endogenous TERT.

Tags

RNA dependent RNA Polymerase Activity

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