Normothermic Ex Situ Heart Perfusion in Working Mode: Assessment of Cardiac Function and Metabolism

13.0K Views

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09:10 min

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January 12th, 2019

DOI :

10.3791/58430-v

January 12th, 2019

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Sanaz Hatami¹, Christopher W. White¹, Martin Ondrus¹, Xiao Qi¹, Max Buchko¹, Sayed Himmat¹, Lily Lin², Katie Cameron³, David Nobes⁴, Hyun-Joong Chung⁵, Jayan Nagendran¹^,⁶, Darren H. Freed¹^,³^,⁶^,⁷

¹Department of Surgery, Faculty of Medicine, University of Alberta, ²Department of Pediatrics, Faculty of Medicine, University of Alberta, ³Department of Biomedical Engineering, Faculty of Medicine, University of Alberta, ⁴Department of Mechanical Engineering, Faculty of Engineering, University of Alberta, ⁵Department of Chemical and Materials Engineering, Faculty of Engineering, University of Alberta, ⁶Canadian National Transplant Research Program, ⁷Department of Physiology, Faculty of Medicine, University of Alberta

Summary

Chapters in this video

0:04

Title

0:55

Blood Collection and Heart Procurement

2:46

Ex Situ Heart Perfusion (ESHP) Apparatus Placement and Perfusion Initiation

5:32

Function Assessment and ESHP Metabolic Assessment

7:01

Results: Representative ESHP Analyses

8:20

Conclusion

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