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In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression

DOI :

10.3791/59235-v

8:54 min

March 29th, 2019

March 29th, 2019

6,585 Views

1Center for Epigenetics, Van Andel Research Institute, 2Amgen

This protocol outlines the steps needed to generate a model system in which the transcription of an endogenous gene of interest can be conditionally controlled in live animals or cells using enhanced lac repressor and/or tet activator systems.

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In Vivo Application

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