Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro

5.1K Views

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00:06 min

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August 28th, 2019

DOI :

10.3791/60044-v

August 28th, 2019

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Sebastian P. Stefani¹^,², Paul P. Breen³, Jorge M. Serrador⁴, Aaron J. Camp¹^,²

¹Discipline of Physiology, Sydney Medical School, University of Sydney, ²Bosch Institute, Sydney Medical School, University of Sydney, ³The MARCS Institute, Western Sydney University, ⁴Department of Pharmacology, Physiology & Neuroscience, Rutgers Biomedical and Health Sciences

Summary

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Stochastic Noise Application

Medial Vestibular Nucleus

Balance Dysfunction Therapeutics

Brainstem Extraction

S ACSF Solution

Sagittal Skin Incision

C 57 Black Six Mouse

Pierson Von Jours

Whole cell Patch Clamp Electrophysiology

Micro Pipettes

Potassium based Internal Solution

Chapters in this video

0:04

Title

0:45

Brainstem Preparation

2:27

Whole-Cell Patch Clamp Electrophysiology

4:10

Sinusoidal and Stochastic Noise Application

4:59

Results: Representative Effects of Sinusoidal and Stochastic Noise on MVN Neuronal Firing Rates and Gains

5:57

Conclusion

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