Inducing Acute Liver Injury in Rats via Carbon Tetrachloride (CCl4) Exposure Through an Orogastric Tube
11.2K Views
•
06:12 min
•
April 28th, 2020
DOI :
April 28th, 2020
•Dmitry Frank*1, Shiri Savir*1, Benjamin F. Gruenbaum2, Israel Melamed3, Julia Grinshpun1, Ruslan Kuts1, Boris Knyazer4, Alexander Zlotnik1, Max Vinokur1, Matthew Boyko1
1Department of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, 2Department of Anesthesiology, Yale University School of Medicine, 3Department of Neurosurgery, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, 4Department of Ophthalmology, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev
Chapters in this video
0:03
Introduction
0:23
Preparing Rats for the Experimental Procedure
1:15
Determination of Serum GOT, GPT and Total Bilirubin Baseline Level
1:44
The Procedure for Induction of Acute Liver Injury in Rats
3:03
Determination of Serum GOT, GPT and Total Bilirubin Level after 24 Hours
3:23
Liver Collection for Histological Examination
4:03
Histological Examination on Rats at Time 24 Hours
4:49
Results
5:38
Conclusion
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