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Chronic Stress Shifts Effort-Related Choice Behavior in a Y-Maze Barrier Task in Mice

DOI :

10.3791/61548-v

August 13th, 2020

August 13th, 2020

10,060 Views

1Department of Psychology, Behavioral and Systems Neuroscience Area, The State University of New Jersey, 2Graduate Program in Neuroscience, Rutgers, The State University of New Jersey

The Y-maze barrier task is a behavior test that examines motivation to expend effort for reward. Here, we discuss testing multiple well-validated chronic stressors including chronic corticosterone and social defeat stress with this behavior, as well as the novel chronic non-discriminatory social defeat stress (CNSDS), which is effective in females.

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