Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

6.1K Views

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08:20 min

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March 31st, 2021

DOI :

10.3791/61773-v

March 31st, 2021

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Sabrina M. Ribeiro*¹, Érick D. O. Fratucelli*¹, Júlia M. Fernandes*², Paula C. P. Bueno²^,³, Alberto José Cavalheiro², Marlise I. Klein¹

¹Department of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University (UNESP), ²Department of Organic Chemistry, Institute of Chemistry, São Paulo State University (UNESP), ³Faculty of Pharmaceutical Sciences of Ribeiraão Preto (FCFRP-USP), Department of Physics and Chemistry, University of São Paulo

Summary

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Ultrasound Extraction

Chapters in this video

0:04

Introduction

0:53

Preparation of Crude Extracts (CE) and Fractions (CEF) to Chemical Profile Analysis and Bioassays

2:26

Bioassay and Anti-microbial Activity

4:10

Validation of Biological Activity and Biological Data Analysis

6:16

Results: The Screening Results of the Twelve Crude Extracts from Three Varieties of C. sylvestris Against S. mutans

7:31

Conclusion

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