Results: Representative Solid Pathologic Cancer Progression on a 3D Cell-Printed Hypoxic Cancer-on-a-Chip
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Hypoxia is a key driver of cancer development that induces genomic instability and tumorigenesis. We demonstrate a method for generating central hypoxia in a solid cancer in vitro based on 3D bioprinting technology. Using this method, a radio hypo
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Hypoxia is a hallmark of tumor microenvironment and plays a crucial role in cancer progression. This article describes the fabrication process of a hypoxic cancer-on-a-chip based on 3D cell-printing technology to recapitulate a hypoxia-related pathology of cancer.