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Fluorescent Leakage Assay to Investigate Membrane Destabilization by Cell-Penetrating Peptide

DOI :

10.3791/62028-v

December 19th, 2020

December 19th, 2020

5,073 Views

1PHYMEDEXP, INSERM U1046 - CNRS UMR 9214 - University of Montpellier

The fluorescence leakage assay is a simple method that enables the investigation of peptide/membrane interactions in order to understand their involvement in several biological processes and especially the ability of cell-penetrating peptides to disturb phospholipids bilayers during a direct cellular translocation process.

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