A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
2.4K Views
•
07:41 min
•
March 8th, 2022
DOI :
March 8th, 2022
•Arman Alberto Sorin Shadaloey1,2, Alcida Karz1,2, Rana S. Moubarak1,2, Praveen Agrawal1,2, Grace Levinson1,2, Kevin Kleffman1,2, Orlando Aristizabal3,4, Iman Osman2,5, Youssef Z. Wadghiri3,4, Eva Hernando1,2
1Department of Pathology, NYU Grossman School of Medicine, 2Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, 3Department of Radiology, NYU Grossman School of Medicine, 4Preclinical Imaging Core, NYU Grossman School of Medicine, 5Ronald Perelman Department of Dermatology, NYU Grossman School of Medicine
Chapters in this video
0:04
Introduction
1:14
Xenograft Implantation
3:11
Staged Survival Surgery and In Vivo Imaging
5:21
Nuclear Mitotic Apparatus Protein (NuMA) Staining
5:57
Results: Investigation of Potential Actors in Melanoma Metastasis
6:38
Conclusion
Related Videos
08:28
Experimental Metastasis Assay
20.2K Views
07:39
The Establishment of a Lung Colonization Assay for Circulating Tumor Cell Visualization in Lung Tissues
9.2K Views
08:49
A 3D Organotypic Melanoma Spheroid Skin Model
15.7K Views
09:42
Assessing Tumor Microenvironment of Metastasis Doorway-Mediated Vascular Permeability Associated with Cancer Cell Dissemination using Intravital Imaging and Fixed Tissue Analysis
8.7K Views
06:09
Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
8.6K Views
07:20
A Novel Stromal Fibroblast-Modulated 3D Tumor Spheroid Model for Studying Tumor-Stroma Interaction and Drug Discovery
9.8K Views
08:18
Analysis of Lymph Node Volume by Ultra-High-Frequency Ultrasound Imaging in the Braf/Pten Genetically Engineered Mouse Model of Melanoma
2.9K Views
06:25
Ex Vivo Culture of Circulating Tumor Cells in the Cerebral Spinal Fluid from Melanoma Patients to Study Melanoma-Associated Leptomeningeal Disease
788 Views
09:44
Generation of Organ-conditioned Media and Applications for Studying Organ-specific Influences on Breast Cancer Metastatic Behavior
8.4K Views
07:31
Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs
17.6K Views
Copyright © 2025 MyJoVE Corporation. All rights reserved