Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma

2.1K Views

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07:47 min

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August 31st, 2022

DOI :

10.3791/63958-v

August 31st, 2022

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Kel Vin Tan*¹^,², Xinxiang Yang*³, Chung Ying Chan², Jingjing Shi¹, Hing-Chiu Chang⁴, Keith Wan-Hang Chiu¹^,⁵, Kwan Man³

¹Department of Diagnostic Radiology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, ²Department of Oncology, MRC Oxford Institute for Radiation Oncology, University of Oxford, ³Department of Surgery, School of Clinical Medicine, HKU-SZH & LKS Faculty of Medicine, The University of Hong Kong, ⁴Department of Biomedical Engineering, The Chinese University of Hong Kong, ⁵Department of Diagnostic and Interventional Radiology, Kwong Wah Hospital

Summary

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Non Invasive PET MR Imaging

Orthotopic Mouse Model

Hepatocellular Carcinoma

Hepatic Artery Ligation

Translational Research

Cell Suspension Injection

Chapters in this video

0:04

Introduction

1:06

Subcutaneous Injection of Human Hepatocellular Carcinoma Cell Lines

1:45

Orthotopic Liver Implantation and Hepatic Artery Ligation

4:00

[¹⁸F] FMISO and [¹⁸F] FDG Injection

4:42

PET/MR Acquisition

5:57

Results: Effect of Hepatic Artery Ligation on Orthotopic Hepatocellular Carcinoma in Mice

7:02

Conclusion

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