Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

3.5K Views

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06:14 min

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February 17th, 2023

DOI :

10.3791/64842-v

February 17th, 2023

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Marta Munar-Bestard¹^,², Oscar Villa¹, Maria del Mar Ferrà-Cañellas¹^,²^,³, Joana Maria Ramis¹^,²^,⁴^,⁵, Marta Monjo¹^,²^,⁴^,⁵

¹Group of Cell Therapy and Tissue Engineering, Research Institute on Health Sciences (IUNICS), University of the Balearic Islands (UIB), ²Balearic Islands Health Research Institute (IdISBa), ³Preclinical Research Department, Labo'Life España, ⁴Departament de Biologia Fonamental i Ciències de la Salut, UIB, ⁵ADEMA School of Dentistry, UIB

Summary

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Periodontitis

Rat Model

Ligature Placement

Lipopolysaccharide Injection

Inflammatory Response

Connective Tissue Loss

Alveolar Bone Resorption

Anesthetic Protocol

Surgical Procedure

Gingival Crevice Fluid GCF

Chapters in this video

0:04

Introduction

0:55

Animal Anesthesia and Procedure Preparation

2:48

Retentive Ligature Technique and Intragingival Pg‐LPS Injection

3:42

Post‐Procedure Follow‐Up

4:47

Results: Analysis of the Alveolar Bone and Maxillary Molars

5:46

Conclusion

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