Name: errors as a means of reducing impulsive food choice
Uploaded: 2016-06-05T14:00:00.000+00:00
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Description: Watch this Scientific Journal Video about Errors as a Means of Reducing Impulsive Food Choice at JoVE.com

授予国内生产总值:这项工作是由Ministero Istruzione UNIVERSITAËRicerca（2010XPMFW4_009 PRIN 2010年，协议号）的Programmi迪Ricerca Scientifica迪Rilevante Interesse Nazionale大街（PRIN）资助。我们也感谢卡特里纳贝尔蒂尼和拉法埃拉马里诺校对书稿和表演视频。

伦理声明:在本协议中描述的所有程序进行开发和测试之后，从博洛尼亚大学心理学系的伦理委员会的伦理批准（见赫尔辛基23,53宣言）。 1.参加者<ol><li>选择健康的年轻成年女性的样本。 <ol><li>征集参与者谁不节食，不服用精神药物，​​免费当前或过去的精神或神经疾病的历史决定的，天真的实验的目的。 </li></ol></li><li>邀请志愿者在安静的房间坐下，并收集他们的人口统计资料，包括性别，年龄，受教育程度，空腹小时，身高和体重。 </li><li>计算参与者的身体质量指数（BMI）45,54,55。 </li></ol> 2.饥饿和动机评级<ol><li>收集有关他们的hunge的感觉受试者的自我评估- [R在上11点李克特量表56,57那一刻。 </li><li>使用类似的比例作为对于自评的动机上一步中使用在那一刻消耗6的食品，一个接一个的之一。选择那些在女性人口高价值欲求其中58-62这些食品（基于文化背景）。 <ol><li>显示六个食物中的照片，随机地，通过使用幻灯片演示程序，从而使它们的外观和尺寸匹配尽可能那些在实字。 </li></ol></li></ol> 3.食品刺激的选择<ol><li>选择，单独为每个参与者，在前面的步骤中的两个最高额定食品。 <ol><li>确保，在集团层面，参与者也同样积极地吃两种食物，即没有在动机评级两个项目之间没有显著差异（见步骤2.2和2.2.1）。 </li></ol></li></ol> 4.尔RORS，以此来提高认知控制<ol><li>使用修改如下两个预选的刺激与两个不同的错误率相关联的错误任务24。 <ol><li>程序并运行与适当的刺激传递软件，如E-总理的任务。任务应该持续至少15分钟。见补充代码文件中的示例脚本。 </li></ol></li><li>包括两种情况，其中一个预测（ 即它提示）犯了一个错误（LE）的可能性很低，即，参与者将做一个小的一些错误，以及一个预测犯下错误的概率高（HE）即，在其中参与者将使误差更大数目的（见步骤4.5.2和4.5.3）。 <ol><li>使用这两个预选食品的线索为LE条件（LEFood）之一;使用其他食品项目为线索对HE条件（HEFood）。点缀，随机，相同数量的两种条件下的试验。 </li></ol></li><li>组任务，使每个试验开始与两个食品项目中的一个的灰度级图像，即，经过1000毫秒，变成有色（转到信号），因此要求受试者响应。 <ol><li>对于试验总数的33％，可变停止信号延迟（SSD）后叠加的彩色图像（停止信号）上的一个红色圆圈（见4.4）相对于围棋信号发生，因此需要受到不响应。 </li><li>一旦出现停止信号，都留在屏幕上通行信号发生（其中主体被允许响应时间）后的1000毫秒的最大响应时间去和停止信号。 </li><li>给予反馈后（见步骤4.4），试验可变刺激间隔（500-2000毫秒）的一个空白屏幕分开。 </li></ol></li><li>指导参与者向围棋信号尽可能快地通过按下按钮响应，并在停止信号时切莫。指导他们所有可能的反馈（ 即 ＆＃39，"正确！&#39;&#39;，&#39;&#39;错误！&#39;&#39;，&#39;&#39;太早了！&#39;&#39;）。 </li><li>通过独立地改变它们的SSD，由一个楼梯算法的装置的基础上，参加者的性能定义为LE和何条件错误可能性。勒拥有更短的固态硬盘，而他有更长的固态硬盘24。 <ol><li>在200毫秒都LE和他在第一围棋信号出现后开始的SSD。 </li><li>在LE过程中，如果对这个问题的避免了停止信号后，按下按钮成功以后的审判5毫秒增加SSD;减少了50毫秒的SSD在其后的审讯中，如果标的失败。 </li><li>在他在，增加对下试50毫秒的SSD如果主题成功，否则，由50毫秒的下一个审判降低SSD如果这个问题出现故障63。 </li></ol></li><li>用于分析，比较去和停止试验和LE和HE条件的准确性和响应时间24。难道不是Consider错过的响应。使用国家统计或其他统计软件进行数据分析。 </li></ol> 5.跨期选择的认知控制措施<ol><li>辖参与者两颞贴现任务，分别在一个平衡的顺序，错误的任务结束后不久（详见下文）。测量在一个时空贴现任务为LEFood主观值，而在其他的HEFood主观值。上运行E-总理或任何其他刺激交付软件的任务。见补充代码文件中的示例脚本。 <ol><li>在每个任务，本参加者，在每个试验中，假想食品25,64,65 40单位，可以可变延迟后得到之间的选择（ 即 ，2天，2周，1个月，3个月，6个月，和1年，总共六个延迟条件25,66,67）和呈现在眼前可用较少量相同的食物。 </li><li>包括五个选择在每个延迟条件。提供的有关六延迟条件跨学科随机顺序选择块。 </li></ol></li><li>指导参与者通过想象在指定的时间接收指定的奖励数额，使这两个选项之间进行选择，并指示按下两个按钮25,68他们的一个偏好。 <ol><li>明确地告诉他们正朝着假设的食物选择参加;有没有正确或不正确的选择，但他们可以自由选择他们最喜欢的选项;他们没有时间限制的决定，但他们应该尽快做出自己的选择，因为他们觉得喜欢一个收获比其他。 </li></ol></li><li>程序的任务，使得对于每个延迟条件下，较小的即时选项的量进行调节，通过反复试验试验的基础上，参加者之前的选择，使用在具有equival立即奖励的量收敛滴定过程耳鼻喉科主观价值作为延迟奖励25,67（参见5.3.1步骤5.3.5到）。 <ol><li>首先，始终提交参加者，对每个延迟条件，以选择20个单位可用"现在"的食物（叮咬），并可以在该特定延迟67相同的食物40单位之间，从而，在每个延迟的第一试条件参与者时刻面临这两个具体数额67之间进行选择。 </li><li>然后，降低，第一选择后，上，如果参加者选择在先前的试验中较小的选项下试越小选项的量，否则，增加下试越小选项的量如果参与者选择了较大的选项以前的审判。 </li><li>减少与连续选择较小的选项的大小调节:第一调整是较小和较大奖励之间的差的一半，而用于后续的选择是在上次调节23的一半。 </li><li>重复该步骤，以上步骤，直到参与者在一个特定的延误病​​情，之后，参与者在其他延误病情开始一个新的一系列的选择了五选择。 </li><li>对于一个块中的每个试验，考虑立即较小金额的较大后奖励的主观价值的最好的猜测。因此，采取将已提出了关于延迟块截至该延迟后奖励的主观价值的估计第六审判的直接量，并使用它为分析（ 即所谓的无差别点;见步骤5.6）25。 </li></ol></li><li>飞度，通过非线性最小二乘分析，双曲型方程V = 1 /（1 + K T）（ 即 V =主观价值; K =常数最合适的; T =时间天延迟）参与者的冷漠23点相互独立的时空贴现任务。在奥德做到这一点R以计算所考虑的每个奖励作为时间69-71功能的主观价值的折现率（K）。使用STATISTICA或者任何其他统计软件来执行该非线性估算。 </li><li>登录变换，以标准化数据的k值，然后运行参数分析23,25。 注:较大的K值对应于一个陡峭的折扣功能，从而表明该科目更倾向于选择在较大的后一个较小的直接选择。 </li><li>通过校正饥饿评级，自我报告问卷得分外部食用线索灵敏度的比较为LEFood和HEFood k个值（见步骤6），和BMI 45,54,55。使用国家统计或其他统计软件进行数据分析。 </li></ol>荷兰饮食行为6.外部饮食行为分量表问卷（DEBQ EEB） <ol><li>使用日ËDEBQ EEB 72衡量志愿者的外部食用线索的敏感性，以控制在实验过程中可能的混杂。 </li></ol> 7.述职<ol><li>汇报参与者在会议结束时实验的目的。问他们是否错误任务过程中不知何故意识到错误操作的，如果他们认为他们以不同的方式在颞贴现任务，根据两种不同的食物选择莫名其妙。 注:关于整个过程的任何印象或感觉（ 例如 ，他们是否认为有两个主要任务之间的关联）的欢迎。 </li></ol>

The authors have nothing to disclose.

本文详细介绍了一种新的协议旨在减少健康的年轻成年女性冲动的食物选择。在这个协议中的关键步骤包括从健康女性人口采样参与者，在实验的时间收集自我报告饥饿程度，选择两种食物具有同等激励值对于每个受试者，在提交参加者的错误任务，其中每个的两个不同的误差似然性（高，低，在各试验无规地散布）与两个预选食品之一相关联，并且分别测量参与者跨期选择每个预选的食物。这?...

如今，关键的是要帮助人们面临饮食失调1-4的崛起。这些疾病反映与食欲的食物，诱使个人寻求并尽快食用它相关的激励动机的高估（这已被证明特别是甜的高脂肪食物5-6）。这发生在的，可能导致被上了一段时间的饮食未来利益为代价，而是要发挥饮食控制的能力是必要的7-8。事实上，不少人显示这些异常行为已经对食用线索9-10和初级奖励11经验，增强激励值升高注意偏向。此外，即使只是在寻找的美味食品可以定位为立即消耗食物的欲望，无论是在与饮食失调的个体和在正常人群12-13。为了从即时满足避免，而不是放弃长期outco我（ 例如 ，饮食几个月后减肥），必须运动量大的自控和抵御先天之本，进化决心冲动给诱惑并立即消费。发挥自我控制，这是相互关联在神经科学领域的认知控制的概念，一个概念，指的是能够克服的先天冲动进一步审议，可能的话，实施其他更恰当的行为14。 个人如何进行自我控制战略？研究发现，人们的能力从自动应答避免错误满语境15加高年。错误是深思熟虑高度唤起和厌恶事件，当遇到，引起代偿反应16。具体来说，他们CUE在性能和实用功能衰竭/损失，以此暗示一个需要过电流和f调节控制水平uture相应的行为17。此外，错误可以提示厌恶学习，以警示方式，从易出错，适应不良行为逃脱，从而诱导的最佳选择反应18-21的实施。 本协议显示了如何美味的食物和错误之间的关系可以用信号，在一定的行为参与将导致成本（ 即 ，奖励损失），从而鼓励代偿自我控制策略的实施，从而减少冲动的食物选择20,22。在改编自23，本协议中，参与者被要求事先自行报告他们的饥饿水平在实验的时间和评价六个不同的食物。根据收视率，两种食物与每个科目等值奖励价值选择为后续任务。然后，参与者执行其中两个以前选择的食物它错误任务（见参考文献24）EMS线索不同错误率（高和低）与性能相关联:该错误任务被编程，使得在一次试验条件下，通过一种食物线索，与会者使一个小数目的错误，并在其它试验条件下，由另一线索食品，它们使错误的数目大得多。随后，参加者为两个主要奖励跨期选择测量（改编自参考25）。寻求更快，而不是满足，面对诱人的食物时，而被节食，确实是由清脆跨期选择捕获这一点至关重要较大，但延迟增援的能力范式26。的时间越长人们需要等待一个好的被接收并消耗时，更这种潜在奖励的主观评价被削弱（ 即所谓的颞贴现现象27-34）。可怜的决定（ 即更倾向于选择关闭的满足，即提高了时间对于未来收益贴现）被认为是冲动35的核心功能和众多障碍，包括吸毒和肥胖36-45的一个里程碑。在接受本协议描述的步骤后，参加展示减少不耐烦选择刺激插入字幕出错率高，选择性。该效果更加明显，当由受试者报告饥饿水平低23。这是因为饥饿通过提高初级奖励的激励值影响的食品46-49即时评价，反过来，这些奖励7,50-52未来的量的折现率。 这种方法的优点首先在于它容易适用性。前述时际决定任务的误差训练是几乎完全不费力，从而有可能在不同的临床设置中使用。第二，该方法产生具有假想食用物品的期望的效果，而不需要使用真正的食物。第三，参与者主要是不知道食品的错误关联，使得对食物的喜好正品，这可能会影响食物可靠的决策在现实生活中，以及后续效应。最后，参加者在研究23测试的都是年轻女性，但有很好的理由推测，在跨期决策食物错误搭配的效果将是对年轻男性同样也是如此，主要是因为在目前的研究对象是不知道的预期的效果。

<table><tbody><tr><td>E-Prime</td><td>PST</td><td></td><td>Stimulus Delivery Software</td></tr><tr><td>Statistica</td><td>Statsoft</td><td></td><td>Statistical Software</td></tr></tbody></table>

errors as a means of reducing impulsive food choice

Nowadays, the increasing incidence of eating disorders due to poor self-control has given rise to increased obesity and other chronic weight problems, and ultimately, to reduced life expectancy. The capacity to refrain from automatic responses is usually high in situations in which making errors is highly likely. The protocol described here aims at reducing imprudent preference in women during hypothetical intertemporal choices about appetitive food by associating it with errors. First, participants undergo an error task where two different edible stimuli are associated with two different error likelihoods (high and low). Second, they make intertemporal choices about the two edible stimuli, separately. As a result, this method decreases the discount rate for future amounts of the edible reward that cued higher error likelihood, selectively. This effect is under the influence of the self-reported hunger level. The present protocol demonstrates that errors, well known as motivationally salient events, can induce the recruitment of cognitive control, thus being ultimately useful in reducing impatient choices for edible commodities.

从上述的协议的应用的代表性结果在这里报告。 错误的任务错误任务的有效性已经通过下面的结果来确定。关于参与者犯下错误的百分比，他们表现出显著更高一些错误的HE比LE条件下，在停止审判比在围棋试验一个显著较高的一些错误，并在停止试验的一个显著更高一些错误在何...

Watch this Scientific Journal Video about Errors as a Means of Reducing Impulsive Food Choice at JoVE.com

Errors as a Means of Reducing Impulsive Food Choice

Giving in to temptation of tasty food may result in long-term overweight problems. This protocol describes how to reduce imprudent preference for edible commodities during hypothetical intertemporal choices in women by associating them with errors.

作为错误脉冲减少食物选择的一种手段

Nowadays, the increasing incidence of eating disorders due to poor self-control has given rise to increased obesity and other chronic weight problems, and ...

errors-as-a-means-of-reducing-impulsive-food-choice

Research

JoVE Journal

Behavior

8.5K 次观看.  Justus-Liebig-Universität Giessen. Giving in to temptation of tasty food may result in long-term overweight problems. This protocol describes how to reduce imprudent preference for edible commodities during hypothetical intertemporal choices in women by associating them with errors.

视频: Errors as a Means of Reducing Impulsive Food Choice

Fat Preference: A Novel Model of Eating Behavior in Rats

Obesity is a growing problem in the United States of America, with more than a third of the population classified as obese. One factor contributing to this multifactorial disorder is the consumption of a high fat diet, a behavior that has been shown to increase both caloric intake and body fat content. However, the elements regulating preference for high fat food over other foods remain understudied.
To overcome this deficit, a model to quickly and easily test changes in the preference for dietary fat was developed. The Fat Preference model presents rats with a series of choices between foods with differing fat content. Like humans, rats have a natural bias toward consuming high fat food, making the rat model ideal for translational studies. Changes in preference can be ascribed to the effect of either genetic differences or pharmacological interventions. This model allows for the exploration of determinates of fat preference and screening pharmacotherapeutic agents that influence acquisition of obesity.

Dietary fat content influences both energy intake and body fat composition in mammals. By examining rats&#8217; preference for high fat food in a series of choice experiments, it is possible to test genetic differences and pharmacological interventions on their preference for high fat food.

脂肪偏好：饮食行为的一种新模型大鼠

Obesity is a growing problem in the United States of America, with more than a third of the population classified as obese. One factor contributing to ...

科研

行为学

A Treatment Package without Escape Extinction to Address Food Selectivity

Feeding difficulties and feeding disorders are a commonly occurring problem for young children, particularly children with developmental delays including autism. Behavior analytic interventions for the treatment of feeding difficulties oftentimes include escape extinction as a primary component of treatment. The use of escape extinction, while effective, may be problematic as it is also associated with the emergence of challenging behavior (e.g., extinction burst). Such challenging behavior may be an acceptable side effect in treatment cases where feeding problems are severe and chronic (e.g., failure to thrive). However, in more acute cases (e.g., selective eating), the negative side effect may be unwarranted and undesired. More recent research on the behavioral treatment of food selectivity has begun to evaluate treatments for feeding difficulties that do not include escape extinction (e.g., demand fading, behavioral momentum), with some success. However, research to date reveals individual differences in responsiveness to such treatments and no clear preferable treatment has emerged. This manuscript describes a multi-component treatment package that includes shaping, sequential presentation and simultaneous presentation, for the treatment of food selectivity in four young children with developmental delays. This treatment package extends the literature on the behavioral treatment for food selectivity and offers a multi-component treatment protocol that may be clinically applicable across a range of treatment scenarios and settings.

Feeding difficulties are a common problem for children with developmental disorders, including autism, and behavioral interventions often include escape extinction. Recent research has begun to evaluate treatments that do not include escape extinction. This manuscript describes a multicomponent treatment package that does not use escape extinction to treat feeding difficulties.

一个疗程装没有逃脱灭绝解决粮食选择性

Feeding difficulties and feeding disorders are a commonly occurring problem for young children, particularly children with developmental delays including ...

Progressive-ratio Responding for Palatable High-fat and High-sugar Food in Mice

Foods that are rich in fat and sugar significantly contribute to over-eating and escalating rates of obesity. The consumption of palatable foods can produce a rewarding effect that strengthens action-outcome associations and reinforces future behavior directed at obtaining these foods. Increasing evidence that the rewarding effects of energy-dense foods play a profound role in overeating and the development of obesity has heightened interest in studying the genes, molecules and neural circuitry that modulate food reward1,2. The rewarding impact of different stimuli can be studied by measuring the willingness to work to obtain them, such as in operant conditioning tasks3. Operant models of food reward measure acquired and voluntary behavioral responses that are directed at obtaining food. A commonly used measure of reward strength is an operant procedure known as the progressive ratio (PR) schedule of reinforcement.4,5 In the PR task, the subject is required to make an increasing number of operant responses for each successive reward. The pioneering study of Hodos (1961) demonstrated that the number of responses made to obtain the last reward, termed the breakpoint, serves as an index of reward strength4. While operant procedures that measure changes in response rate alone cannot separate changes in reward strength from alterations in performance capacity, the breakpoint derived from the PR schedule is a well-validated measure of the rewarding effects of food. The PR task has been used extensively to assess the rewarding impact of drugs of abuse and food in rats (e.g.,6-8), but to a lesser extent in mice9. The increased use of genetically engineered mice and diet-induced obese mouse models has heightened demands for behavioral measures of food reward in mice. In the present article we detail the materials and procedures used to train mice to respond (lever-press) for a high-fat and high-sugar food pellets on a PR schedule of reinforcement. We show that breakpoint response thresholds increase following acute food deprivation and decrease with peripheral administration of the anorectic hormone leptin and thereby validate the use of this food-operant paradigm in mice.

The present report details the protocol employed to measure the rewarding effects of high-fat food in mice using a progressive ratio operant conditioning task.

累进比率响应小鼠可口的高脂肪和高糖食品

Foods that are rich in fat and sugar significantly contribute to over-eating and escalating rates of obesity. The consumption of palatable foods can ...

神经科学

Control of Eating Behavior Using a Novel Feedback System

Subjects eat food from a plate that sits on a scale connected to a computer that records the weight loss of the plate during the meal and makes up a curve of food intake, meal duration and rate of eating modeled by a quadratic equation. The purpose of the method is to change eating behavior by providing visual feedback on the computer screen that the subject can adapt to because her/his own rate of eating appears on the screen during the meal. The data generated by the method is automatically analyzed and fitted to the quadratic equation using a custom made algorithm. The method has the advantage of recording eating behavior objectively and offers the possibility of changing eating behavior both in experiments and in clinical practice. A limitation may be that experimental subjects are affected by the method. The same limitation may be an advantage in clinical practice, as eating behavior is more easily stabilized by the method. A treatment that uses this method has normalized body weight and restored the health of several hundred patients with anorexia nervosa and other eating disorders and has reduced the weight and improved the health of severely overweight patients.

Subjects eat food from a plate placed on a scale connected to a computer that records the weight loss of the plate during the meal. Feedback on the computer screen allows the subject to adapt her/his eating behavior to reference curves thus normalizing body weight.

用一种新的反馈系统控制进食行为

Subjects eat food from a plate that sits on a scale connected to a computer that records the weight loss of the plate during the meal and makes up a curve ...

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats

The present article provides a guide for the conduction and analysis of three conditioning-based protocols to evaluate impulsivity in rats. Impulsivity is a meaningful concept because it is associated with psychiatric conditions in humans and with maladaptive behavior in non-human animals. It is believed that impulsivity is composed of separate factors. There are laboratory protocols devised to assess each of these factors using standardized automated equipment. Delay discounting is associated with the incapacity to be motivated by delayed outcomes. This factor is evaluated through intertemporal choice protocols, which consist&#160;of presenting the individual with a choice situation involving an immediate reward and a larger but delayed reward. Response inhibition deficit is associated with the incapacity to withhold prepotent responses. Differential reinforcement of low rates (DLR) and feature-negative discrimination protocols assess the response inhibition deficit factor of impulsivity. The former imposes a condition to a motivated individual in which most wait a minimum period of time for a response to be rewarded. The latter evaluates the capacity of individuals to refrain from food seeking responses when a signal of the absence of food is presented. The purpose of these protocols is to construct an objective quantitative measure of impulsivity, which serves to make cross-species comparisons, allowing the possibility of translational research. The advantages of these particular protocols include their easy set-up and application, which stems from the relatively small amount of equipment needed and the automated nature of these protocols.

We present three protocols that assess different forms of impulsivity in rats and other small mammals. Intertemporal choice procedures evaluate the tendency to discount the value of delayed outcomes. Differential reinforcement of low rates and feature-negative discrimination evaluate response inhibition capacity with and without punishment for inappropriate responses, respectively.

评估大鼠冲动不同表现的三个实验室程序

The present article provides a guide for the conduction and analysis of three conditioning-based protocols to evaluate impulsivity in rats. Impulsivity is ...

Methods for Presenting Real-world Objects Under Controlled Laboratory Conditions

Our knowledge of human object vision is based almost exclusively on studies in which the stimuli are presented in the form of computerized two-dimensional (2-D) images. In everyday life, however, humans interact predominantly with real-world solid objects, not images. Currently, we know very little about whether images of objects trigger similar behavioral or neural processes as do real-world exemplars. Here, we present methods for bringing the real-world into the laboratory. We detail methods for presenting rich, ecologically-valid real-world stimuli under tightly-controlled viewing conditions. We describe how to match closely the visual appearance of real objects and their images, as well as novel apparatus and protocols that can be used to present real objects and computerized images on successively interleaved trials. We use a decision-making paradigm as a case example in which we compare willingness-to-pay (WTP) for real snack foods versus 2-D images of the same items. We show that WTP increases by 6.6% for food items displayed as real objects versus high-resolution 2-D colored&#160;images of the same foods -suggesting that real foods are perceived as being more valuable than their images. Although presenting real object stimuli under controlled conditions presents several practical challenges for the experimenter, this approach will fundamentally expand our understanding of the cognitive and neural processes that underlie naturalistic vision.

We describe methods for presenting real-world objects and matched images of the same objects under tightly-controlled experimental conditions. The methods are described in the context of a decision-making task, but the same real-world approach can be extended to other cognitive domains such as perception, attention, and memory.

在受控实验室条件下呈现真实物体的方法

Our knowledge of human object vision is based almost exclusively on studies in which the stimuli are presented in the form of computerized two-dimensional ...

Concept Development and Use of an Automated Food Intake and Eating Behavior Assessment Method

The vast majority of dietary and eating behavior assessment methods are based on self-reports. They are burdensome and also prone to measurement errors. Recent technological innovations allow for the development of more accurate and precise dietary and eating behavior assessment tools that require less effort for both the user and the researcher. Therefore, a new sensor-based device to assess food intake and eating behavior was developed. The device is a regular dining tray equipped with a video camera and three separate built-in weighing stations. The weighing stations measure the weight of the bowl, plate, and drinking cup continuously over the course of a meal. The video camera positioned to the face records eating behavior characteristics (chews, bites), which are analyzed using artificial intelligence (AI)-based automatic facial expression software. The tray weight and the video data are transported at real-time to a personal computer (PC) using a wireless receiver. The outcomes of interest, such as the amount eaten, eating rate and bite size, can be calculated by subtracting the data of these measures at the timepoints of interest. The information obtained by the current version of the tray can be used for research purposes, an upgraded version of the device would also facilitate the provision of more personalized advice on dietary intake and eating behavior. Contrary to the conventional dietary assessment methods, this dietary assessment device measures food intake directly within a meal and is not dependent on memory or the portion size estimation. Ultimately, this device is therefore suited for daily main meal food intake and eating behavior measures. In the future, this technology based dietary assessment method can be linked to health applications or smart watches to obtain a complete overview of exercise, energy intake, and eating behavior.

This protocol shows and explains a new technology-based dietary assessment method. The method consists of a dining tray with multiple built-in weighing scales and a video camera. The device is unique in the sense that it incorporates automated measures of food and drink intake and eating behavior over the course of a meal.

自动食物摄入和饮食行为评估方法的概念开发和使用

The vast majority of dietary and eating behavior assessment methods are based on self-reports. They are burdensome and also prone to measurement errors. ...

<meta charset="utf8"></head><body>使用可口的食物获取小鼠模型研究暴饮暴食症

Intermittent Binge-Intake Model in Mice

Obesity affects one in eight individuals globally. Overeating, especially high-calorie foods, plays a significant role in obesity. Binge eating disorder (BED) is a complex condition caused by a combination of biological, psychological, and social factors. It involves excessive consumption of high-calorie foods in a short period and is often linked to anxiety and cravings.
Here, we present a protocol employing continuous and intermittent access to a new highly palatable food (HPF) -- M&amp;M&#39;s -- to develop a mouse model for investigating binge eating disorder (BED). The HPF, chosen for its high fat and sugar content, represents an optimal food source to study due to its strong palatability, which makes it particularly suited for examining compulsive eating behaviors. Using C57BL/6 mice, we provided continuous or intermittent access to M&amp;M&#39;s while allowing unrestricted access to standard chow and water. By the 8th day, the mice in the intermittent access group exhibited pronounced binge-eating behaviors, which persisted through the 26th day. These mice also consumed significantly more calories -- predominantly from the confectionary -- than those in the continuous access and control groups. The contrast between continuous and intermittent access underscores the critical role of feeding schedules in promoting the overconsumption of palatable foods.
Furthermore, behavioral assessments revealed intermittent access to the HPF-induced anxiety-like behaviors, highlighting the psychological impact of access patterns on both eating behavior and emotional states. By incorporating these two distinct feeding paradigms, this study offers valuable insights into how the availability of highly palatable foods can exacerbate binge-eating tendencies. This model provides a more realistic approach to studying binge-eating behaviors and their metabolic consequences. It highlights the importance of standardized models in biomedical research. Our findings offer insights into the physiological and neural mechanisms underlying BED, which could pave the way for developing effective therapeutic interventions for BED and obesity.

<meta charset="utf8"></head><body>作者聚焦:用于研究暴食症的基于 M&M 的可访问小鼠模型 - 对饮食行为、焦虑和神经机制的见解

A binge-eating model was established in mice using intermittent access to M&amp;M's (a highly palatable food made of fat and sugar). Mice with intermittent access to this high-fat, high-sugar food showed stress-like behaviors, increased caloric intake, and a preference for that food over standard chow compared to mice with continuous or no access to the food.

小鼠间歇性暴饮暴食模型

Obesity affects one in eight individuals globally. Overeating, especially high-calorie foods, plays a significant role in obesity. Binge eating disorder ...

作为错误脉冲减少食物选择的一种手段

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此视频中的章节

脂肪偏好：饮食行为的一种新模型大鼠

一个疗程装没有逃脱灭绝解决粮食选择性

累进比率响应小鼠可口的高脂肪和高糖食品

用一种新的反馈系统控制进食行为

评估大鼠冲动不同表现的三个实验室程序

在受控实验室条件下呈现真实物体的方法

自动食物摄入和饮食行为评估方法的概念开发和使用

小鼠间歇性暴饮暴食模型

小鼠间歇性暴饮暴食模型

小鼠间歇性暴饮暴食模型