Results: Assessment of an Orthotopic Mouse Tumor Model for Human Glioblastoma Multiforme
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Conclusion
副本
We describe the optimal technique for intracranial injection of GEM-derived glioblastoma cells into an immunocompetent mouse brain resulting in tumors that recapitulate key features of human glioblastoma. This technique for orthotopic injection of
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Here, we describe a preclinical orthotopic mouse model for GBM, established by intracranial injection of cells derived from genetically engineered mouse model tumors. This model displays the disease hallmarks of human GBM. For translational studies, the mouse brain tumor is tracked by in vivo MRI and histopathology.
