Chapter 21
Drugs for Peptic Ulcer Disease
Fisiopatología de la enfermedad ulcerosa péptica: factores lesivos
Peptic ulcers are sores in the mucosa of the stomach or duodenum.
The mucosal epithelium houses acid-secreting parietal and gastrin-secreting G cells.
The ...
Fisiopatología de la enfermedad ulcerosa péptica: factores de defensa de las mucosas
Peptic ulcer disease, or PUD, involves discontinuous gastrointestinal tract lining due to gastric acid or pepsin secretion.
The mucus-bicarbonate barrier ...
Medicamentos supresores de la acidez para la enfermedad ulcerosa péptica: inhibidores de la bomba de protones
Two of the main contributors to peptic ulcer formation are H. pylori infections or NSAID use, both facilitating gastric acid production.
Gastric acid is ...
Medicamentos supresores de la acidez en la úlcera péptica: antagonistas del receptor H_2 de histamina
Histamine H2 receptors are G protein-coupled receptors located on the basolateral membrane of parietal cells.
Histamine released from ECL cells binds to ...
Medicamentos supresores de la acidez para la enfermedad de úlcera péptica: antiácidos
In the gastric lumen, increased acid secretion can form or exacerbate ulcers in the mucosal layer.
Carbonate antacids, like sodium bicarbonate and calcium ...
Medicamentos para la enfermedad de úlcera péptica: sucralfato como agente protector de las mucosas
Recall that increased acid secretion in the gastric lumen disrupts mucosal defense mechanisms and weakens the mucus-bicarbonate barrier.
This enables ...
Medicamentos para la enfermedad ulcerosa péptica: análogos de prostaglandinas como agentes protectores de la mucosa
The gastric mucosa majorly produces prostaglandin E2 and I2 to protect cells from mucosal injury.
These bind to EP3 receptors, which couple with ...
Tratamiento de la bacteria Helicobacter pylori en las úlceras pépticas: terapia antimicrobiana
Helicobacter pylori or H. pylori, a gram-negative bacillus, thrives in the stomach's acidic environment, impairing somatostatin production. This ...
ACERCA DE JoVE
Copyright © 2025 MyJoVE Corporation. Todos los derechos reservados