Results: Mass Histology Allows for Large-scale Analysis of Neurodegeneation in Drosophila
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Conclusion
Transcripción
The overall goal of this procedure is to quantify Neurodegeneration in the Drosophila Brain, caused by a variety of factors including age, genetic modifications, or environmental influences, without the need for specific staining. This method is v
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Drosophila is widely used as a model system to study neurodegeneration. This protocol describes a method by which degeneration, as determined by vacuole formation in the brain, can be quantified. It also minimizes effects due to the experimental procedure by processing and sectioning control and experimental flies as one sample.