Neurological Severity Score and Infarct Volume Measurement
1:56
Sucrose Preference Test
2:44
Porsolt s Forced-swim Test
3:26
Results: Proof of Occlusion
4:14
Conclusion
Transcription
Our protocol proposes a new medial cerebral artery occlusion technique in rats to help study the mechanism of post-stroke depression development and to find a more efficient therapy. The main advantage of our technique is its ability to reduce the
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Here we present a protocol to induce post-stroke depression in rats by occluding the middle cerebral artery via the internal carotid artery. We use the Porsolt forced swim test and the sucrose preference test to confirm and evaluate induced depressive moods.