This model can help to improve our understanding of the mechanism involved in lung injury and to test halogenated agent as potential novel therapy for acute respiratory distress syndrome. The main advantage of this technique is that inhaled anesth
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We describe a model of hydrochloric acid-induced acute respiratory distress syndrome (ARDS) in piglets receiving sedation with halogenated agents, isoflurane and sevoflurane, through a device used for inhaled intensive care sedation. This model can be used to investigate the biological mechanisms of halogenated agents on lung injury and repair.