For a compound that needs to be given directly into the bloodstream, optimizing intravenous administration is the key part of the experimental procedure. Our detailed protocol provides step-by-step instructions to carry out multiple intravenous bo
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This protocol provides a step-by-step procedure for executing multiple intravenous bolus dose administration and invasive hemodynamic monitoring in mice. Investigators can use this protocol for future therapeutic compound screening for pulmonary artery hypertension.