April 29th, 2014
•Models of spontaneous metastatic renal cell carcinoma (RCC) disease progression can be used for evaluating treatments in a clinically relevant setting. This protocol demonstrates different procedures for orthotopic kidney tumor cell implantation, proper nephrectomy, and finally outlines a necropsy guide for visual and bioluminescent scoring of metastatic burden and localization.
Tags
Related Videos
Single Port Donor Nephrectomy
Modeling Stroke in Mice - Middle Cerebral Artery Occlusion with the Filament Model
Mammary Transplantation of Stromal Cells and Carcinoma Cells in C57BL/6J Mice
Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma
Modeling Intracerebral Hemorrhage in Mice: Injection of Autologous Blood or Bacterial Collagenase
Generation of Subcutaneous and Intrahepatic Human Hepatocellular Carcinoma Xenografts in Immunodeficient Mice
Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery
Modeling Chemotherapy Resistant Leukemia In Vitro
Assessment of Kidney Function in Mouse Models of Glomerular Disease
Copyright © 2024 MyJoVE Corporation. 판권 소유