Heat Precipitation in a Heat Exchanger and Bag Filtration of Plant Extract
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Results
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Conclusion
필기록
The overall goal of this set of experiments is to precipitate plant host cell proteins using heat. Thus facilitating subsequent chromatographic purification of recombinant biopharmaceutical proteins. This method can help to streamline process deve
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Three heat precipitation methods are presented that effectively remove more than 90% of host cell proteins (HCPs) from tobacco extracts prior to any other purification step. The plant HCPs irreversibly aggregate at temperatures above 60 °C.