The Use of Trace Eyeblink Classical Conditioning to Assess Hippocampal Dysfunction in a Rat Model of Fetal Alcohol Spectrum Disorders

DOI :

10.3791/55350-v

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19:57 min

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August 5th, 2017

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7,994 Views

Tuan D. Tran^1,2, Aenia Amin^1,2, Keith G. Jones², Ellen M. Sheffer¹, Lidia Ortega¹, Keith Dolman²

¹Department of Psychology, East Carolina University, ²Multidisciplinary Studies Program in Neuroscience, East Carolina University

Chapters

Trace eyeblink classical conditioning (ECC) was used to assess hippocampal-dependent associative learning in adult rats that were administered a high concentration (11.9% v/v) of alcohol during early neonatal brain development. In general, ECC procedures are sound diagnostic tools for detecting brain dysfunction across many psychological and biomedical settings.

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