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Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

1.0K Views

08:57 min

May 17th, 2024

DOI :

10.3791/65740-v

May 17th, 2024


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Malignant Peripheral Nerve Sheath Tumors

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0:00

Introduction

1:28

Identifying Neurofibromas and Malignant Peripheral Nerve Sheath Tumors (MPNSTs) in P0-GGFβ3 Mice

2:42

Preparing Hematoxylin and Eosin‐Stained Sections of Grossly Visible Tumors

4:16

Identifying Potential Plexiform Neurofibromas (PNs)and Malignant Peripheral Nerve Sheath Tumors (MPNSTs)by Performing Special Stains to Confirm Diagnoses

6:36

Verifying the Identity of Early‐Passage MPNST Cells and Allograft of Early‐Passage Tumor Cells to Demonstrate Tumorigenicity

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