Whole‐Cell Patch‐Clamp Recording of the IKv in Voltage‐Clamp Mode
6:43
Results: IKv in H9c2 Cells
7:37
Conclusion
Transkript
This protocol successfully records the effects of the aconitine on the IKv of H9C2 cells. Promoting new phases for investigating the mechanism of cardiotoxicity of drugs from the perspective of ion channels. The whole-cell patch-clamp technique is
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The present protocol describes an efficient method for the real-time and dynamic acquisition of voltage-gated potassium (Kv) channel currents in H9c2 cardiomyocytes using the whole-cell patch-clamp technique.