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Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers

DOI :

10.3791/50638-v

October 17th, 2013

October 17th, 2013

45,410 Views

1Fischell Department of Bioengineering, University of Maryland, 2Institute for Bioscience and Biotechnology Research, University of Maryland

Many therapeutic applications require safe and efficient transport of drug carriers and their cargoes across cellular barriers in the body. This article describes an adaptation of established methods to evaluate the rate and mechanism of transport of drug nanocarriers (NCs) across cellular barriers, such as the gastrointestinal (GI) epithelium.

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